Allergic reaction to intravenous atropine in a patient with organophosphate poisoning

Atropine is a drug of choice for muscarinic effects in organophosphate (OP) poisoning. Allergic reaction to atropine is rare. Here, we report a case of a 17-year-old male who was admitted with clinical manifestations of acute OP poisoning. After intravenous atropine injection, cutaneous signs of hyp...

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Bibliographic Details
Main Authors: Shiva Samsamshariat, Navid Honarjoo, Farzad Gheshlaghi, Gholamali Dorvashy, Nastaran Eizadi-Mood
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Research in Pharmacy Practice
Subjects:
Online Access:http://www.jrpp.net/article.asp?issn=2319-9644;year=2019;volume=8;issue=1;spage=33;epage=34;aulast=Samsamshariat
Description
Summary:Atropine is a drug of choice for muscarinic effects in organophosphate (OP) poisoning. Allergic reaction to atropine is rare. Here, we report a case of a 17-year-old male who was admitted with clinical manifestations of acute OP poisoning. After intravenous atropine injection, cutaneous signs of hypersensitivity including erythema and urticarial were observed on his body. Atropine injection was stopped, and antihistamines and hydrocortisone were administered. His condition was improved, and he discharged with a good condition after 2 days hospitalization. Adverse allergic reaction to atropine should be in mind when managing OP poisoning cases.
ISSN:2319-9644
2279-042X