Chemical Constituents of <i>Anacardium occidentale</i> as Inhibitors of <i>Trypanosoma cruzi</i> Sirtuins

Chemical Constituents of <i>Anacardium occidentale</i> as Inhibitors of <i>Trypanosoma cruzi</i> Sirtuins

Benznidazole and nifurtimox, the only drugs available for the treatment of Chagas disease, have limited efficacy and have been associated with severe adverse side effects. Thus, there is an urgent need to find new biotargets for the identification of novel bioactive compounds against the parasite an...

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Bibliographic Details
Main Authors: Tanira Matutino Bastos, Helena Mannochio Russo, Nilmar Silvio Moretti, Sergio Schenkman, Laurence Marcourt, Mahabir Prashad Gupta, Jean-Luc Wolfender, Emerson Ferreira Queiroz, Milena Botelho Pereira Soares
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Molecules
Subjects:
<i>Trypanosoma cruzi</i>
sirtuins
<i>Anacardium occidentale</i>
drug discovery
Online Access:https://www.mdpi.com/1420-3049/24/7/1299

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