Genome-Wide Alteration of 5-Hydroxymethylcytosine in Hypoxic-Ischemic Neonatal Rat Model of Cerebral Palsy

Genome-Wide Alteration of 5-Hydroxymethylcytosine in Hypoxic-Ischemic Neonatal Rat Model of Cerebral Palsy

Cerebral palsy (CP) is a neurodevelopmental disorder usually occurring early in life and persisting through the whole life. Several risk factors, including perinatal hypoxia-ischemia (HI), may contribute to occurrence of CP in preterm infants. DNA hydroxymethylation has been shown to play an importa...

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Bibliographic Details
Main Authors: Yunpeng Zhang, Yaodong Zhang, Danmei Chen, Cuiting Wang, Long Chen, Chao Gao, Wei Fan, Jimin Shi, Jihong Zhang, Bing Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
cerebral palsy
hypoxic-ischemic injury
5-hydroxymethylcytosine
DNA hydroxymethylation
Tet
neurodevelopment
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00214/full

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