AZFa candidate gene UTY and its X homologue UTX are expressed in human germ cells

The Ubiquitous Transcribed Y (UTY a.k.a. KDM6C) AZFa candidate gene on the human Y chromosome and its paralog on the X chromosome, UTX (a.k.a. KDM6A), encode a histone lysine demethylase removing chromatin H3K27 methylation marks at genes transcriptional start sites for activation. Both proteins har...

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Bibliographic Details
Main Authors: Peter H Vogt, Jutta Zimmer, Ulrike Bender, Thomas Strowitzki
Format: Article
Language:English
Published: Bioscientifica 2021-06-01
Series:Reproduction and Fertility
Subjects:
Online Access:https://raf.bioscientifica.com/view/journals/raf/aop/raf-20-0049/raf-20-0049.xml