Transient Silencing of a Type IV P-Type ATPase, Atp10c, Results in Decreased Glucose Uptake in C2C12 Myotubes

Transient Silencing of a Type IV P-Type ATPase, Atp10c, Results in Decreased Glucose Uptake in C2C12 Myotubes

Atp10c is a strong candidate gene for diet-induced obesity and type 2 diabetes. To identify molecular and cellular targets of ATP10C, Atp10c expression was altered in vitro in C2C12 skeletal muscle myotubes by transient transfection with an Atp10c-specific siRNA. Glucose uptake assays revealed that...

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Bibliographic Details
Main Authors:	S. E. Hurst, S. C. Minkin, J. Biggerstaff, M. S. Dhar
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	Journal of Nutrition and Metabolism
Online Access:	http://dx.doi.org/10.1155/2012/152902

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