Association of genetic variation in the <it>NR1H4</it> gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease

Association of genetic variation in the <it>NR1H4</it> gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease

<p>Abstract</p> <p>Background</p> <p>Pathogenesis of inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn’s disease (CD), involves interaction between environmental factors and inappropriate immune responses in the intestine of genetically predisposed in...

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Bibliographic Details
Main Authors: Attinkara Ragam, Mwinyi Jessica, Truninger Kaspar, Regula Jaroslaw, Gaj Pawel, Rogler Gerhard, Kullak-Ublick Gerd A, Eloranta Jyrki J
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Research Notes
Subjects:
Bile acid homeostasis
Crohn’s disease
Farnesoid X receptor
Inflammatory bowel disease
Single nucleotide polymorphisms
Ulcerative colitis
Online Access:http://www.biomedcentral.com/1756-0500/5/461

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http://www.biomedcentral.com/1756-0500/5/461

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