Modular Nanotransporters for Nuclear-Targeted Delivery of Auger Electron Emitters
This review describes artificial modular nanotransporters (MNTs) delivering their cargos into target cells and then into the nuclei – the most vulnerable cell compartment for most anticancer agents and especially for radionuclides emitting short-range particles. The MNT strategy uses natural subcell...
Main Author: | Alexander S. Sobolev |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-08-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2018.00952/full |
Similar Items
-
Antitumor Activity of Auger Electron Emitter 111In Delivered by Modular Nanotransporter for Treatment of Bladder Cancer With EGFR Overexpression
by: Andrey A. Rosenkranz, et al.
Published: (2018-11-01) -
Targeted Delivery of 111In Into the Nuclei of EGFR Overexpressing Cells via Modular Nanotransporters With Anti-EGFR Affibody
by: Tatiana S. Karyagina, et al.
Published: (2020-03-01) -
Editorial: Delivery of Locally-Acting Agents to Intracellular Targets
by: Andrey A. Rosenkranz, et al.
Published: (2020-09-01) -
Preparation, cytotoxicity, and in vivo antitumor efficacy of 111In-labeled modular nanotransporters
by: Slastnikova TA, et al.
Published: (2017-01-01) -
Optical 3D-Nanometry to Study the Function of Biomolecular Motors in Nanotransport
by: Nitzsche, Bert
Published: (2009)