Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma

Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma

Paraneoplastic bullous pemphigoid is a rare paraneoplastic syndrome. Rash is pruritic, with erythematous eruption of large subepidermal bullae over skin and often mucosal surfaces. We present an 84y woman with a three week history of erythematous rash, and 48hrs of bullae. A left clear cell renal ce...

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Main Authors: Stuart R. Jackson, Jakob Koestenbauer, Adam P. Carroll, Than-Htike Oo, Shaun Chou, Balasubramaniam Indrajit
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Urology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442020300073
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spelling doaj-e7aa8263ad8d4fa6a8f6b2b889db28df2020-11-25T02:57:57ZengElsevierUrology Case Reports2214-44202020-05-0130Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinomaStuart R. Jackson0Jakob Koestenbauer1Adam P. Carroll2Than-Htike Oo3Shaun Chou4Balasubramaniam Indrajit5Dubbo Base Hospital, Myall St, Dubbo, NSW, 2830, Australia; University of Sydney, NSW, Australia; Corresponding author. Dubbo Base Hospital, Myall St, Dubbo, NSW, 2830, Australia.Dubbo Base Hospital, Myall St, Dubbo, NSW, 2830, AustraliaDubbo Base Hospital, Myall St, Dubbo, NSW, 2830, AustraliaDubbo Base Hospital, Myall St, Dubbo, NSW, 2830, AustraliaDubbo Base Hospital, Myall St, Dubbo, NSW, 2830, AustraliaDubbo Base Hospital, Myall St, Dubbo, NSW, 2830, AustraliaParaneoplastic bullous pemphigoid is a rare paraneoplastic syndrome. Rash is pruritic, with erythematous eruption of large subepidermal bullae over skin and often mucosal surfaces. We present an 84y woman with a three week history of erythematous rash, and 48hrs of bullae. A left clear cell renal cell carcinoma was identified on CT imaging during the presentation. Subsequent removal of the tumour resulted in resolution of bullous pemphigoid symptoms. This first-of-kind case and successful result strengthens the association between renal cell carcinoma and paraneoplastic bullous pemphigoid, arguing for a high degree of clinical suspicion in unexplained presentations of bullous pemphigoid.http://www.sciencedirect.com/science/article/pii/S2214442020300073
collection DOAJ
language English
format Article
sources DOAJ
author Stuart R. Jackson
Jakob Koestenbauer
Adam P. Carroll
Than-Htike Oo
Shaun Chou
Balasubramaniam Indrajit
spellingShingle Stuart R. Jackson
Jakob Koestenbauer
Adam P. Carroll
Than-Htike Oo
Shaun Chou
Balasubramaniam Indrajit
Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma
Urology Case Reports
author_facet Stuart R. Jackson
Jakob Koestenbauer
Adam P. Carroll
Than-Htike Oo
Shaun Chou
Balasubramaniam Indrajit
author_sort Stuart R. Jackson
title Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma
title_short Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma
title_full Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma
title_fullStr Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma
title_full_unstemmed Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma
title_sort paraneoplastic bullous pemphigoid – a sign of clear cell renal carcinoma
publisher Elsevier
series Urology Case Reports
issn 2214-4420
publishDate 2020-05-01
description Paraneoplastic bullous pemphigoid is a rare paraneoplastic syndrome. Rash is pruritic, with erythematous eruption of large subepidermal bullae over skin and often mucosal surfaces. We present an 84y woman with a three week history of erythematous rash, and 48hrs of bullae. A left clear cell renal cell carcinoma was identified on CT imaging during the presentation. Subsequent removal of the tumour resulted in resolution of bullous pemphigoid symptoms. This first-of-kind case and successful result strengthens the association between renal cell carcinoma and paraneoplastic bullous pemphigoid, arguing for a high degree of clinical suspicion in unexplained presentations of bullous pemphigoid.
url http://www.sciencedirect.com/science/article/pii/S2214442020300073
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