A defective CXCL16/CXCR6 axis increases the risk of pregnancy loss via the abnormal crosstalk between decidual γδ t cells and trophoblasts

A defective CXCL16/CXCR6 axis increases the risk of pregnancy loss via the abnormal crosstalk between decidual γδ t cells and trophoblasts

Objective: The maternal–fetal interface undergoes dynamic changes to allow the fetus to grow and develop in the uterus. The interaction between decidual γδ Τ cells and trophoblasts plays a pivotal role during successful pregnancy; however, their physiological functions in early-term human pregnancy...

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Bibliographic Details
Main Authors: Deng-Xuan Fan, Ming-Qing Li, Wen-Jie Zhou, Hong-Lan Huang, Hui-Li Yang, Cong-Jian Xu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Reproductive and Developmental Medicine
Subjects:
cxcl16; cxcr6; decidual γδ t cells; maternal–fetal interface; recurrent spontaneous abortion; trophoblasts
Online Access:http://www.repdevmed.org/article.asp?issn=2096-2924;year=2021;volume=5;issue=3;spage=129;epage=139;aulast=Fan

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