Influence of Molecular Weight and Degree of Deacetylation of Low Molecular Weight Chitosan on the Bioactivity of Oral Insulin Preparations

Influence of Molecular Weight and Degree of Deacetylation of Low Molecular Weight Chitosan on the Bioactivity of Oral Insulin Preparations

The objective of the present study was to prepare and characterize low molecular weight chitosan (LMWC) with different molecular weight and degrees of deacetylation (DDA) and to optimize their use in oral insulin nano delivery systems. Water in oil nanosized systems containing LMWC-insulin polyelec...

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Bibliographic Details
Main Authors: Nidal A. Qinna, Qutuba G. Karwi, Nawzat Al-Jbour, Mayyas A. Al-Remawi, Tawfiq M. Alhussainy, Khaldoun A. Al-So'ud, Mahmoud M. H. Al Omari, Adnan A. Badwan
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Marine Drugs
Subjects:
insulin
oral delivery
oligochitosan
low molecular weight chitosan
nanoparticles
spectroscopy
glucose
diabetic rats
Online Access:http://www.mdpi.com/1660-3397/13/4/1710

Internet

http://www.mdpi.com/1660-3397/13/4/1710

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