Hyaluronic Acid Present in the Tumor Microenvironment Can Negate the Pro-apototic Effect of a Recombinant Fragment of Human Surfactant Protein D on Breast Cancer Cells

Hyaluronic Acid Present in the Tumor Microenvironment Can Negate the Pro-apototic Effect of a Recombinant Fragment of Human Surfactant Protein D on Breast Cancer Cells

Human surfactant protein D (SP-D) belongs to the family of collectins that is composed of a characteristic amino-terminal collagenous region and a carboxy-terminal C-type lectin domain. Being present at the mucosal surfaces, SP-D acts as a potent innate immune molecule and offers protection against...

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Bibliographic Details
Main Authors: Valarmathy Murugaiah, Chiara Agostinis, Praveen M. Varghese, Beatrice Belmonte, Salvatore Vieni, Fanan A. Alaql, Salman H. Alrokayan, Haseeb A. Khan, Anuvinder Kaur, Terry Roberts, Taruna Madan, Roberta Bulla, Uday Kishore
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
innate immunity
surfactant protein D
immune surveillance
breast cancer
hyaluronic acid
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01171/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01171/full

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