Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand

Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand

Alkynes are amongst the most valuable functional groups in organic chemistry, however, the preparation of alkyl-substituted alkynes still remains elusive. Here the authors show a nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts.

Bibliographic Details
Main Authors: Xingjie Zhang, Di Qi, Chenchen Jiao, Xiaopan Liu, Guisheng Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25222-1
Description
Summary:Alkynes are amongst the most valuable functional groups in organic chemistry, however, the preparation of alkyl-substituted alkynes still remains elusive. Here the authors show a nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts.
ISSN:2041-1723

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