Recent Strategic Advances in CFTR Drug Discovery: An Overview

Cystic fibrosis transmembrane conductance regulator (CFTR)-rescuing drugs have already transformed cystic fibrosis (CF) from a fatal disease to a treatable chronic condition. However, new-generation drugs able to bind CFTR with higher specificity/affinity and to exert stronger therapeutic benefits a...

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Bibliographic Details
Main Authors: Marco Rusnati, Pasqualina D’Ursi, Nicoletta Pedemonte, Chiara Urbinati, Robert C. Ford, Elena Cichero, Matteo Uggeri, Alessandro Orro, Paola Fossa
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/7/2407