Ascl1 as a novel player in the Ptf1a transcriptional network for GABAergic cell specification in the retina.
In contrast with the wealth of data involving bHLH and homeodomain transcription factors in retinal cell type determination, the molecular bases underlying neurotransmitter subtype specification is far less understood. Using both gain and loss of function analyses in Xenopus, we investigated the put...
Main Authors: | Nicolas Mazurier, Karine Parain, Damien Parlier, Silvia Pretto, Johanna Hamdache, Philippe Vernier, Morgane Locker, Eric Bellefroid, Muriel Perron |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3958475?pdf=render |
Similar Items
-
Ptf1a triggers GABAergic neuronal cell fates in the retina
by: Parain Karine, et al.
Published: (2007-10-01) -
Prdm13 forms a feedback loop with Ptf1a and is required for glycinergic amacrine cell genesis in the Xenopus Retina
by: Nathalie Bessodes, et al.
Published: (2017-09-01) -
Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum
by: Nakamura, Shoko
Published: (2011) -
Ptf1a is expressed transiently in all types of amacrine cells in the embryonic zebrafish retina
by: Harris William A, et al.
Published: (2009-09-01) -
FOXO3 Shares Common Targets with ASCL1 Genome-wide and Inhibits ASCL1-Dependent Neurogenesis
by: Ashley E. Webb, et al.
Published: (2013-08-01)