Autophagy modulation altered differentiation capacity of CD146+ cells toward endothelial cells, pericytes, and cardiomyocytes

Autophagy modulation altered differentiation capacity of CD146+ cells toward endothelial cells, pericytes, and cardiomyocytes

Abstract Background To date, many attempts are employed to increase the regenerative potential of stem cells. In this study, we evaluated the hypothesis of whether an autophagy modulation could alter differentiation potency of CD146+ cells into mature pericyte, endothelial, and cardiomyocyte lineage...

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Bibliographic Details
Main Authors: Mehdi Hassanpour, Jafar Rezaie, Masoud Darabi, Amirataollah Hiradfar, Reza Rahbarghazi, Mohammad Nouri
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
Human bone marrow CD146+ cells
Autophagy modulation
Nitrosative assay
Lineage-specific differentiation
Exosome activity
Online Access:http://link.springer.com/article/10.1186/s13287-020-01656-0

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http://link.springer.com/article/10.1186/s13287-020-01656-0

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