Synergistic Induction of Macrophage Inflammatory Protein-3α/CCL20 Production by Interleukin-17A and Tumor Necrosis Factor-αin Nasal Polyp Fibroblasts

Synergistic Induction of Macrophage Inflammatory Protein-3α/CCL20 Production by Interleukin-17A and Tumor Necrosis Factor-αin Nasal Polyp Fibroblasts

Background: Accumulation of T cells and immature dendritic cells (DCs) is one of the characteristic features of nasal polyps. However, the question remains why these cells accumulate in nasal polyp tissue. Macrophage inflammatory protein-3α (MIP-3α/CCL20) is a chemokine involved in the migration of...

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Main Authors: Manabu Nonaka, MD, PhD, Nozomu Ogihara, MD, Akira Fukumoto, MD, PhD, Atsuko Sakanushi, MD, Kaoru Kusama, MD, Ruby Pawankar, MD, PhD, Toshiaki Yagi, MD, PhD
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:World Allergy Organization Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S193945511930554X

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