Efficacy and Safety of Ivabradine Once-Daily Prolonged-Release versus Twice-Daily Immediate-Release Formulation in Patients with Stable Chronic Heart Failure with Systolic Dysfunction: A Randomized, Double-Blind, Phase 3 Non-Inferiority (PROFICIENT) Study

Efficacy and Safety of Ivabradine Once-Daily Prolonged-Release versus Twice-Daily Immediate-Release Formulation in Patients with Stable Chronic Heart Failure with Systolic Dysfunction: A Randomized, Double-Blind, Phase 3 Non-Inferiority (PROFICIENT) Study

Abstract Introduction Dosing frequency is an important factor influencing medication compliance in patients with heart failure (HF), which in turn is imperative in achieving the desired therapeutic outcome. Here we assessed the efficacy and safety of ivabradine prolonged-release (PR) once-daily (tes...

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Bibliographic Details
Main Authors: Ajit Mullasari, The PROFICIENT investigators
Format: Article
Language:English
Published: Adis, Springer Healthcare 2020-10-01
Series:Cardiology and Therapy
Subjects:
Heart failure
Heart rate
Immediate-release
Ivabradine
Once-daily
Prolonged-release systolic dysfunction
Online Access:https://doi.org/10.1007/s40119-020-00200-8

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