Molecular interplay between ion channels and the regulation of apoptosis

Molecular interplay between ion channels and the regulation of apoptosis

Apoptosis is the programmed and deliberate destruction of specific cells. This process occurs during normal development and maintains cellular homeostasis. Disruption or malfunction of apoptosis is implicated in diseases like cancer, AIDS as well as neurodegenerative disorders. The movement of monov...

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Main Authors: MONA A RAZIK, JOHN A CIDLOWSKI
Format: Article
Language:English
Published: BMC 2002-01-01
Series:Biological Research
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200011
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spelling doaj-e787cfae2f384db7b988fe817e00c8962020-11-25T01:56:31ZengBMCBiological Research0716-97600717-62872002-01-01352203207Molecular interplay between ion channels and the regulation of apoptosisMONA A RAZIKJOHN A CIDLOWSKIApoptosis is the programmed and deliberate destruction of specific cells. This process occurs during normal development and maintains cellular homeostasis. Disruption or malfunction of apoptosis is implicated in diseases like cancer, AIDS as well as neurodegenerative disorders. The movement of monovalent ions appears to set the stage for the induction of the self-destruction machinery by creating an intracellular environment that favors activation and coordinated execution of the apoptotic program. Understanding the components and steps involved in this intricate process can further our insight to diseases and reveal new approaches for therapeutic treatmenthttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200011
collection DOAJ
language English
format Article
sources DOAJ
author MONA A RAZIK
JOHN A CIDLOWSKI
spellingShingle MONA A RAZIK
JOHN A CIDLOWSKI
Molecular interplay between ion channels and the regulation of apoptosis
Biological Research
author_facet MONA A RAZIK
JOHN A CIDLOWSKI
author_sort MONA A RAZIK
title Molecular interplay between ion channels and the regulation of apoptosis
title_short Molecular interplay between ion channels and the regulation of apoptosis
title_full Molecular interplay between ion channels and the regulation of apoptosis
title_fullStr Molecular interplay between ion channels and the regulation of apoptosis
title_full_unstemmed Molecular interplay between ion channels and the regulation of apoptosis
title_sort molecular interplay between ion channels and the regulation of apoptosis
publisher BMC
series Biological Research
issn 0716-9760
0717-6287
publishDate 2002-01-01
description Apoptosis is the programmed and deliberate destruction of specific cells. This process occurs during normal development and maintains cellular homeostasis. Disruption or malfunction of apoptosis is implicated in diseases like cancer, AIDS as well as neurodegenerative disorders. The movement of monovalent ions appears to set the stage for the induction of the self-destruction machinery by creating an intracellular environment that favors activation and coordinated execution of the apoptotic program. Understanding the components and steps involved in this intricate process can further our insight to diseases and reveal new approaches for therapeutic treatment
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200011
work_keys_str_mv AT monaarazik molecularinterplaybetweenionchannelsandtheregulationofapoptosis
AT johnacidlowski molecularinterplaybetweenionchannelsandtheregulationofapoptosis
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