The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control
Primary cultures of hepatocytes are powerful models in studying the sequence of events that are necessary for cell progression from a G0-like state to S phase. The models mimic the physiological process of hepatic regeneration after liver injury or partial hepatectomy. Many reports suggest that the...
Main Authors: | Jean-Philippe Guégan, Christophe Frémin, Georges Baffet |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
|
Series: | International Journal of Hepatology |
Online Access: | http://dx.doi.org/10.1155/2012/328372 |
Similar Items
-
From basic research to clinical development of MEK1/2 inhibitors for cancer therapy
by: Meloche Sylvain, et al.
Published: (2010-02-01) -
Cardiac Hormones Target the Ras-MEK 1/2-ERK 1/2 Kinase Cancer Signaling Pathways
by: David L. Vesely
Published: (2011-03-01) -
Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway
by: Niluka Gunawardhana, et al.
Published: (2018-01-01) -
Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling
by: Rakshamani Tripathi, et al.
Published: (2020-10-01) -
Functional Redundancy of ERK1 and ERK2 MAP Kinases during Development
by: Christophe Frémin, et al.
Published: (2015-08-01)