Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function
Objective:The aim of this study was to compare Tc-99m dimercaptosuccinic acid (99mTc-DMSA) renal cortical scintigraphy and Tc-99m diethylene triamine pentaacetic acid (99mTc-DTPA) and Tc-99m mercaptoacetyltriglycine (99mTc-MAG3) dynamic renal scintigraphy in the evaluation of relative renal function...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Galenos Yayinevi
2020-06-01
|
Series: | Journal of Urological Surgery |
Subjects: | |
Online Access: |
http://jurolsurgery.org/archives/archive-detail/article-preview/comparison-of-sup99m-suptc-dmsa-sup99m-suptc-dtpa-/38523
|
id |
doaj-e76ac7a4586e47bfa6c284d2069c077d |
---|---|
record_format |
Article |
spelling |
doaj-e76ac7a4586e47bfa6c284d2069c077d2020-11-25T03:24:57ZengGalenos YayineviJournal of Urological Surgery2148-95802148-95802020-06-017213013310.4274/jus.galenos.2019.310713049054Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal FunctionFadime Demir0Mustafa Demir1 Tokat Gaziosmanpaşa University Faculty of Medicine, Department of Nuclear Medicine, Tokat, Turkiye Fırat University Faculty of Medicine, Department of Nephrology, Elazığ, Turkiye Objective:The aim of this study was to compare Tc-99m dimercaptosuccinic acid (99mTc-DMSA) renal cortical scintigraphy and Tc-99m diethylene triamine pentaacetic acid (99mTc-DTPA) and Tc-99m mercaptoacetyltriglycine (99mTc-MAG3) dynamic renal scintigraphy in the evaluation of relative renal function (RRF).Materials and Methods:Forty seven patients with renal cortical scintigraphy (with 99mTc-DMSA) and dynamic renal scintigraphy (with 99mTc-DTPA or 99mTc-MAG3) were included in this retrospective study. RRF obtained from 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 scintigraphies, clinical and demographic data were statistically analyzed.Results:There was a high correlation between 99mTc-DMSA renal cortical scintigraphy and dynamic renal scintigraphy (99mTc-DTPA or 99mTc-MAG3) in terms of RRF evaluation (r=0.981, p<0.001 and r=0.918, p=<0.001, respectively). While the Bland Altman plot showed an average difference of 3.30 between RRFs measured by 99mTc-DMSA and by 99mTc-DTPA, the difference between that with 99mTc-DMSA and 99mTc-MAG3 was 0.08.Conclusion:In conclusion, this study showed a high level of compliance between 99mTc-DMSA renal scintigraphy and dynamic renal scintigraphy (99mTc or 99mTc-MAG3) in the evaluation of RRF. Time loss, radiation exposed to the patients and economic losses are minimized with the use of a single method suitable for the purpose. http://jurolsurgery.org/archives/archive-detail/article-preview/comparison-of-sup99m-suptc-dmsa-sup99m-suptc-dtpa-/38523 relative renal function99mtc-dmsa renal cortical scintigraphydynamic renal scintigraphy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Fadime Demir Mustafa Demir |
spellingShingle |
Fadime Demir Mustafa Demir Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function Journal of Urological Surgery relative renal function 99mtc-dmsa renal cortical scintigraphy dynamic renal scintigraphy |
author_facet |
Fadime Demir Mustafa Demir |
author_sort |
Fadime Demir |
title |
Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function |
title_short |
Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function |
title_full |
Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function |
title_fullStr |
Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function |
title_full_unstemmed |
Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function |
title_sort |
comparison of 99mtc-dmsa, 99mtc-dtpa and 99mtc-mag3 renal scintigraphy in the calculation of relative renal function |
publisher |
Galenos Yayinevi |
series |
Journal of Urological Surgery |
issn |
2148-9580 2148-9580 |
publishDate |
2020-06-01 |
description |
Objective:The aim of this study was to compare Tc-99m dimercaptosuccinic acid (99mTc-DMSA) renal cortical scintigraphy and Tc-99m diethylene triamine pentaacetic acid (99mTc-DTPA) and Tc-99m mercaptoacetyltriglycine (99mTc-MAG3) dynamic renal scintigraphy in the evaluation of relative renal function (RRF).Materials and Methods:Forty seven patients with renal cortical scintigraphy (with 99mTc-DMSA) and dynamic renal scintigraphy (with 99mTc-DTPA or 99mTc-MAG3) were included in this retrospective study. RRF obtained from 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 scintigraphies, clinical and demographic data were statistically analyzed.Results:There was a high correlation between 99mTc-DMSA renal cortical scintigraphy and dynamic renal scintigraphy (99mTc-DTPA or 99mTc-MAG3) in terms of RRF evaluation (r=0.981, p<0.001 and r=0.918, p=<0.001, respectively). While the Bland Altman plot showed an average difference of 3.30 between RRFs measured by 99mTc-DMSA and by 99mTc-DTPA, the difference between that with 99mTc-DMSA and 99mTc-MAG3 was 0.08.Conclusion:In conclusion, this study showed a high level of compliance between 99mTc-DMSA renal scintigraphy and dynamic renal scintigraphy (99mTc or 99mTc-MAG3) in the evaluation of RRF. Time loss, radiation exposed to the patients and economic losses are minimized with the use of a single method suitable for the purpose. |
topic |
relative renal function 99mtc-dmsa renal cortical scintigraphy dynamic renal scintigraphy |
url |
http://jurolsurgery.org/archives/archive-detail/article-preview/comparison-of-sup99m-suptc-dmsa-sup99m-suptc-dtpa-/38523
|
work_keys_str_mv |
AT fadimedemir comparisonof99mtcdmsa99mtcdtpaand99mtcmag3renalscintigraphyinthecalculationofrelativerenalfunction AT mustafademir comparisonof99mtcdmsa99mtcdtpaand99mtcmag3renalscintigraphyinthecalculationofrelativerenalfunction |
_version_ |
1724598835932561408 |