Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function

Objective:The aim of this study was to compare Tc-99m dimercaptosuccinic acid (99mTc-DMSA) renal cortical scintigraphy and Tc-99m diethylene triamine pentaacetic acid (99mTc-DTPA) and Tc-99m mercaptoacetyltriglycine (99mTc-MAG3) dynamic renal scintigraphy in the evaluation of relative renal function...

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Main Authors: Fadime Demir, Mustafa Demir
Format: Article
Language:English
Published: Galenos Yayinevi 2020-06-01
Series:Journal of Urological Surgery
Subjects:
Online Access: http://jurolsurgery.org/archives/archive-detail/article-preview/comparison-of-sup99m-suptc-dmsa-sup99m-suptc-dtpa-/38523
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spelling doaj-e76ac7a4586e47bfa6c284d2069c077d2020-11-25T03:24:57ZengGalenos YayineviJournal of Urological Surgery2148-95802148-95802020-06-017213013310.4274/jus.galenos.2019.310713049054Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal FunctionFadime Demir0Mustafa Demir1 Tokat Gaziosmanpaşa University Faculty of Medicine, Department of Nuclear Medicine, Tokat, Turkiye Fırat University Faculty of Medicine, Department of Nephrology, Elazığ, Turkiye Objective:The aim of this study was to compare Tc-99m dimercaptosuccinic acid (99mTc-DMSA) renal cortical scintigraphy and Tc-99m diethylene triamine pentaacetic acid (99mTc-DTPA) and Tc-99m mercaptoacetyltriglycine (99mTc-MAG3) dynamic renal scintigraphy in the evaluation of relative renal function (RRF).Materials and Methods:Forty seven patients with renal cortical scintigraphy (with 99mTc-DMSA) and dynamic renal scintigraphy (with 99mTc-DTPA or 99mTc-MAG3) were included in this retrospective study. RRF obtained from 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 scintigraphies, clinical and demographic data were statistically analyzed.Results:There was a high correlation between 99mTc-DMSA renal cortical scintigraphy and dynamic renal scintigraphy (99mTc-DTPA or 99mTc-MAG3) in terms of RRF evaluation (r=0.981, p<0.001 and r=0.918, p=<0.001, respectively). While the Bland Altman plot showed an average difference of 3.30 between RRFs measured by 99mTc-DMSA and by 99mTc-DTPA, the difference between that with 99mTc-DMSA and 99mTc-MAG3 was 0.08.Conclusion:In conclusion, this study showed a high level of compliance between 99mTc-DMSA renal scintigraphy and dynamic renal scintigraphy (99mTc or 99mTc-MAG3) in the evaluation of RRF. Time loss, radiation exposed to the patients and economic losses are minimized with the use of a single method suitable for the purpose. http://jurolsurgery.org/archives/archive-detail/article-preview/comparison-of-sup99m-suptc-dmsa-sup99m-suptc-dtpa-/38523 relative renal function99mtc-dmsa renal cortical scintigraphydynamic renal scintigraphy
collection DOAJ
language English
format Article
sources DOAJ
author Fadime Demir
Mustafa Demir
spellingShingle Fadime Demir
Mustafa Demir
Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function
Journal of Urological Surgery
relative renal function
99mtc-dmsa renal cortical scintigraphy
dynamic renal scintigraphy
author_facet Fadime Demir
Mustafa Demir
author_sort Fadime Demir
title Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function
title_short Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function
title_full Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function
title_fullStr Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function
title_full_unstemmed Comparison of 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 Renal Scintigraphy in the Calculation of Relative Renal Function
title_sort comparison of 99mtc-dmsa, 99mtc-dtpa and 99mtc-mag3 renal scintigraphy in the calculation of relative renal function
publisher Galenos Yayinevi
series Journal of Urological Surgery
issn 2148-9580
2148-9580
publishDate 2020-06-01
description Objective:The aim of this study was to compare Tc-99m dimercaptosuccinic acid (99mTc-DMSA) renal cortical scintigraphy and Tc-99m diethylene triamine pentaacetic acid (99mTc-DTPA) and Tc-99m mercaptoacetyltriglycine (99mTc-MAG3) dynamic renal scintigraphy in the evaluation of relative renal function (RRF).Materials and Methods:Forty seven patients with renal cortical scintigraphy (with 99mTc-DMSA) and dynamic renal scintigraphy (with 99mTc-DTPA or 99mTc-MAG3) were included in this retrospective study. RRF obtained from 99mTc-DMSA, 99mTc-DTPA and 99mTc-MAG3 scintigraphies, clinical and demographic data were statistically analyzed.Results:There was a high correlation between 99mTc-DMSA renal cortical scintigraphy and dynamic renal scintigraphy (99mTc-DTPA or 99mTc-MAG3) in terms of RRF evaluation (r=0.981, p<0.001 and r=0.918, p=<0.001, respectively). While the Bland Altman plot showed an average difference of 3.30 between RRFs measured by 99mTc-DMSA and by 99mTc-DTPA, the difference between that with 99mTc-DMSA and 99mTc-MAG3 was 0.08.Conclusion:In conclusion, this study showed a high level of compliance between 99mTc-DMSA renal scintigraphy and dynamic renal scintigraphy (99mTc or 99mTc-MAG3) in the evaluation of RRF. Time loss, radiation exposed to the patients and economic losses are minimized with the use of a single method suitable for the purpose.
topic relative renal function
99mtc-dmsa renal cortical scintigraphy
dynamic renal scintigraphy
url http://jurolsurgery.org/archives/archive-detail/article-preview/comparison-of-sup99m-suptc-dmsa-sup99m-suptc-dtpa-/38523
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