Challenging the One-hour Sepsis Bundle

In April 2018, the Surviving Sepsis Campaign (SSC) released an updated sepsis bundle, which combines directives previously listed in the three-hour and six-hour bundles. The authors discussed the reasoning and evidence supporting these changes. However, there are data that suggest these recommendati...

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Bibliographic Details
Main Authors: Annahieta Kalantari, Salim R. Rezaie
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2019-02-01
Series:Western Journal of Emergency Medicine
Online Access:https://escholarship.org/uc/item/72w8j3fh
Description
Summary:In April 2018, the Surviving Sepsis Campaign (SSC) released an updated sepsis bundle, which combines directives previously listed in the three-hour and six-hour bundles. The authors discussed the reasoning and evidence supporting these changes. However, there are data that suggest these recommendations may be contrary to the best available evidence. Our purpose here is to highlight the areas where evidence is only as strong as the methodological constructs of the research used. This article is a narrative review of the available, limited evidence on which the one-hour bundle was based.
ISSN:1936-9018