MALAT1 Modulates TGF-β1-Induced Endothelial-to-Mesenchymal Transition through Downregulation of miR-145

MALAT1 Modulates TGF-β1-Induced Endothelial-to-Mesenchymal Transition through Downregulation of miR-145

Background/Aims: Endothelial-to-mesenchymal transition (EndMT) plays significant roles under various pathological conditions including cardiovascular diseases, fibrosis, and cancer. EndMT of endothelial progenitor cells (EPCs) contributes to neointimal hyperplasia following cell therapy Metastasis-a...

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Bibliographic Details
Main Authors: Yin Xiang, Yachen Zhang, Yong Tang, Qianhui Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
MALAT1
miR-145
Endothelial progenitor cells
Endothelial-to-mesenchymal transition
TGFBR2
SMAD3
Online Access:http://www.karger.com/Article/FullText/477479

Internet

http://www.karger.com/Article/FullText/477479

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