Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote homolog detection

<p>Abstract</p> <p>Background</p> <p>Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This unique ability makes NMF a potentially promising method for biological...

Full description

Bibliographic Details
Main Authors: Lee Soo-Young, Lee Jaehyung, Jung Inkyung, Kim Dongsup
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/298