Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response

Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response

Abstract Background Patient-derived organoids and xenografts (PDXs) have emerged as powerful models in functional diagnostics with high predictive power for anticancer drug response. However, limitations such as engraftment failure and time-consuming for establishing and expanding PDX models followe...

Full description

Bibliographic Details
Main Authors: Feifei Zhang, Wenjie Wang, Yuan Long, Hui Liu, Jijun Cheng, Lin Guo, Rongyu Li, Chao Meng, Shan Yu, Qingchuan Zhao, Shun Lu, Lili Wang, Haitao Wang, Danyi Wen
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Cancer Communications
Subjects:
Personalized cancer therapy
Cancer precision medicine
Patient-derived xenograft (PDX)
MiniPDX
Drug response
In vivo
Online Access:http://link.springer.com/article/10.1186/s40880-018-0329-5

Internet

http://link.springer.com/article/10.1186/s40880-018-0329-5

Similar Items