Increased microRNA-34c abundance in Alzheimer’s disease circulating blood plasma

Increased microRNA-34c abundance in Alzheimer’s disease circulating blood plasma

Circulating microRNAs, present either in the cellular component, peripheral blood mononuclear cells (PBMC), or in cell-free plasma, have emerged as biomarkers for age-dependent systemic, disease-associated changes in many organs. Previously, we have shown that microRNA (miR)-34a is increased in circ...

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Bibliographic Details
Main Authors: Shephali eBhatnagar, Howard eChertkow, Hyman M Schipper, Vikranth eShetty, Zongfei eYuan, Timothy eJones, Samantha eJenkins, Eugenia eWang
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Alzheimer's disease
miR-34a
synaptic dysfunction
peripheral blood mononuclear cells
neuronal survival
plasma microRNA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00002/full

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