Genome analysis of coxsackievirus B1 isolates during the consecutive alternating administration course of triple antiviral combination in newborn mice

Background We developed a new approach for the treatment of enterovirus infections, the consecutive alternating administration (CAA) of a combination of enterovirus inhibitors. On the model of coxsackievirus B1 (CVB1) in mice, two phenomena were observed: absence of drug resistance and increased sus...

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Bibliographic Details
Main Authors: Petar Grozdanov, Marie-Line Joffret, Adelina Stoyanova, Patsy Polston, Emna Achouri, Ivanka Nikolova, Francis Delpeyroux, Angel S Galabov
Format: Article
Language:English
Published: SAGE Publishing 2020-02-01
Series:Antiviral Chemistry & Chemotherapy
Online Access:https://doi.org/10.1177/2040206620906061