Genome analysis of coxsackievirus B1 isolates during the consecutive alternating administration course of triple antiviral combination in newborn mice
Background We developed a new approach for the treatment of enterovirus infections, the consecutive alternating administration (CAA) of a combination of enterovirus inhibitors. On the model of coxsackievirus B1 (CVB1) in mice, two phenomena were observed: absence of drug resistance and increased sus...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-02-01
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Series: | Antiviral Chemistry & Chemotherapy |
Online Access: | https://doi.org/10.1177/2040206620906061 |