PARP-1 overexpression contributes to Cadmium-induced death in rat proximal tubular cells via parthanatos and the MAPK signalling pathway

PARP-1 overexpression contributes to Cadmium-induced death in rat proximal tubular cells via parthanatos and the MAPK signalling pathway

Abstract Parthanatos is a newly discovered form of PARP-1-dependent programmed cell death. It has been reported to play an important role in several cancer or tumour cells; however, few studies have been performed in normal cells. Cadmium is a highly toxic pollutant and is reported to induce autopha...

Full description

Bibliographic Details
Main Authors: Tongwang Luo, Yan Yuan, Qi Yu, Gang Liu, Mengfei Long, Kanglei Zhang, Jianchun Bian, Jianhong Gu, Hui Zou, Yi Wang, Jiaqiao Zhu, Xuezhong Liu, Zongping Liu
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04555-2

Similar Items

Similar Items