Novel AlkB dioxygenases--alternative models for in silico and in vivo studies.

Novel AlkB dioxygenases--alternative models for in silico and in vivo studies.

<h4>Background</h4>ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly contributing to tumor format...

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Main Authors: Damian Mielecki, Dorota Ł Zugaj, Anna Muszewska, Jan Piwowarski, Aleksandra Chojnacka, Marcin Mielecki, Jadwiga Nieminuszczy, Marcin Grynberg, Elżbieta Grzesiuk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22291995/?tool=EBI

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