Two-tier supramolecular encapsulation of small molecules in a protein cage

Protein cages are used for encapsulation of macromolecules such as proteins and nucleic acids. Here, the authors report a strategy to encapsulate poorly soluble small molecules within porous protein cages through capsid-templated micelle formation and show that the resulting lipoprotein-like cages e...

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Bibliographic Details
Main Authors: Thomas G. W. Edwardson, Stephan Tetter, Donald Hilvert
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19112-1