Summary: | In 2014, we celebrated 130 anniversary of Grawitz’s report suggesting that the renal carcinoma originates from intrarenal adrenal rests and the name «hypernehproma» was subsequently accepted. The discussions continued until the middle of 20th century when electron microscopic studies finally approved the Virchow’s postulates and showed that the renal tumors originate from the canalicular epithelium. This period became to be also a keystone for uropathology as independent sub-specialization in pathology.During that period numerous classification of male genital tract tumors were accepted, as well as the histological grading of the tumors, which started to be a part of routine medical practice. The invention of immunohistochemistry and new cytogenetic techniques affected a great influence and increased the significance of role of pathologist in detailed assessment and standardization of morphological criteria of urological tumors.Side by side, the wide applying of blood test for prostatic specific antigen (PSA) and invention of fineneedle prostatic biopsy technique were performed. The results of this technological breakthrough influenced dramatically to worldwide clinical practice. Such increased clinical interest for early diagnosis and treatment of prostatic cancer made push to wide range of scientific investigations, concerning the morphology of prostate. Due to rapid growth of knowledge about etiology and pathogenesis, as well as biological behavior the different urological malignancies, the significance of multidisciplinary teams (MDT) with participation of urologists, oncologists and pathologists is essential. Such co-operation in urological oncology provides better understanding of the patient’s status, his tumor diagnosis, stage and treatment of the patient. Therefore, participation of the pathologist is the as equal among equals. Such teams can offer more detailed consideration and modern attitude to the oncological problems and can help to design new directions that will be useful to both, patients and clinical physicians (oncologists and urologists), as well as diagnostic pathologists. This co-operation will rapidly increase the self-awareness of the pathologist as ‘diagnostic oncologist’. These multidisciplinary teams might be a good example for other specializations in practical medicine and the organization of such teams and there guidance to the everyday practice is the main aim of this article.
|