An Efficient Protocol for the Synthesis of Carboacyclic Nucleosides via Aza-Conjugate Addition Reaction

An Efficient Protocol for the Synthesis of Carboacyclic Nucleosides via Aza-Conjugate Addition Reaction

A new efficient method for the synthesis of carboacyclic nucleosides as biologically interesting compounds via aza-conjugate addition of pyrimidine nucleobases to a,β-unsaturated esters in the presence of catalytic amount of LiOH.H2O (1.2-4.8 mol%) under microwave irradiation is described. This meth...

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Bibliographic Details
Main Authors: Mohammad Ali Zolfigol, Ardeshir Khazaei, Ahmad Reza Moosavi-Zare, Abdolkarim Zare, Ali Reza Hasanijejad
Format: Article
Language:English
Published: Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR 2010-12-01
Series:Iranian Journal of Chemistry & Chemical Engineering
Subjects:
carboacyclic nucleoside
aza-conjugate addition reaction
pyrimidine nucleobase
-unsaturated ester
microwave
Online Access:http://www.ijcce.ac.ir/article_6406_af1dd59e7f68c78ceed0b21ff2e77e8b.pdf

Internet

http://www.ijcce.ac.ir/article_6406_af1dd59e7f68c78ceed0b21ff2e77e8b.pdf

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