CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity.

CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity.

Rickettsia typhi is an intracellular bacterium that causes endemic typhus, a febrile disease that can be fatal due to complications including pneumonia, hepatitis and meningoencephalitis, the latter being a regular outcome in T and B cell-deficient C57BL/6 RAG1-/- mice upon Rickettsia typhi infectio...

Full description

Bibliographic Details
Main Authors: Kristin Moderzynski, Stefanie Papp, Jessica Rauch, Liza Heine, Svenja Kuehl, Ulricke Richardt, Bernhard Fleischer, Anke Osterloh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5119731?pdf=render

Internet

http://europepmc.org/articles/PMC5119731?pdf=render

Similar Items