The Red Queen in mitochondria: cyto-nuclear co-evolution, hybrid breakdown and human disease

Cyto-nuclear incompatibility, a specific form of Dobzhansky-Muller incompatibility caused by incompatible alleles between mitochondrial and nuclear genomes, has been suggested to play a critical role during speciation. Several features of the mitochondrial genome (mtDNA), including high mutation rat...

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Bibliographic Details
Main Authors: Jui-Yu eChou, Jun-Yi eLeu
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00187/full