C-Peptide Inhibits Decidualization in Human Endometrial Stromal Cells via GSK3β-PP1

Decidualization refers to the functional differentiation of endometrial stromal cells and plays a significant role in embryo implantation and pregnancy. C-peptide is excreted in equimolar concentrations as that of insulin during the metabolism of proinsulin in pancreatic beta-cells. High levels of C...

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Bibliographic Details
Main Authors: Sana Abdul Khaliq, Mi-Ock Baek, Hye-Jeong Cho, Seung Joo Chon, Mee-Sup Yoon
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
PP1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.609551/full