The dark side of opioids in pain management: basic science explains clinical observation

Abstract. Introduction:. In the past 2 decades, opioids have been used increasingly for the treatment of persistent pain, and doses have tended to creep up. As basic science elucidates mechanisms of pain and analgesia, the cross talk between central pain and opioid actions becomes clearer. Objective...

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Bibliographic Details
Main Authors: Cyril Rivat, Jane Ballantyne
Format: Article
Language:English
Published: Wolters Kluwer 2016-08-01
Series:PAIN Reports
Online Access:http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000570