Hypoglycaemic effect of alcoholic extract of olive (Olea europaea L.) leaf in healthy and diabetic rats

In traditional medicine leaves of olive (Olea europaea L.) are used as a diuretic, hypotensive, antibacterial and antiatherosclerotic. In the present study, oral administration of 0.1, 0.25 and 0.5g/kg body wt. of the alcoholic extract of leaves of olive for 14 days on the level of glucose and insul...

Full description

Bibliographic Details
Main Authors:	A Eidi, M Eidi, SH Oryan, F Fallahyan, R Darzi Darounkala
Format:	Article
Language:	English
Published:	Institue of Medicinal Plants, ACECR 2004-11-01
Series:	Journal of Medicinal Plants
Subjects:	olea europaea hypoglycaemic diabetes rat
Online Access:	http://jmp.ir/article-1-726-en.html

id	doaj-e7260c24df234d2baa98cf5b94444c04
record_format	Article
spelling	doaj-e7260c24df234d2baa98cf5b94444c042021-09-19T04:33:13ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582004-11-013123640Hypoglycaemic effect of alcoholic extract of olive (Olea europaea L.) leaf in healthy and diabetic ratsA Eidi0M Eidi1SH Oryan2F Fallahyan3R Darzi Darounkala4 Biology Department, Science Faculty, Science & Research Campus, Islamic Azad University, Tehran, Iran Biology Department, Science Faculty, Varamin Unit, Islamic Azad University, Tehran, Iran Biology Department, Science Faculty, Teacher Training University, Tehran, Iran Biology Department, Science Faculty, Science & Research Campus, Islamic Azad University, Tehran, Iran Biology Department, Science Faculty, Science & Research Campus, Islamic Azad University, Tehran, Iran In traditional medicine leaves of olive (Olea europaea L.) are used as a diuretic, hypotensive, antibacterial and antiatherosclerotic. In the present study, oral administration of 0.1, 0.25 and 0.5g/kg body wt. of the alcoholic extract of leaves of olive for 14 days on the level of glucose and insulin in healthy and streptozotocin-induced diabetic rats were evaluated. The results showed that oral administration of the alcoholic extract of olive exhibited a significant reduction in blood glucose and increased plasma insulin in diabetic rats. The extract didnot change the level of blood glucose and plasma insulin in healthy rats significantly. A comparison was made between the action of the alcoholic extract and a known antidiabetic drug, glibenclamide (600 g/kg body wt.). The hypoglycaemic effect of the extract was greater than that observed with glibenclamide.http://jmp.ir/article-1-726-en.htmlolea europaeahypoglycaemicdiabetesrat
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	A Eidi M Eidi SH Oryan F Fallahyan R Darzi Darounkala
spellingShingle	A Eidi M Eidi SH Oryan F Fallahyan R Darzi Darounkala Hypoglycaemic effect of alcoholic extract of olive (Olea europaea L.) leaf in healthy and diabetic rats Journal of Medicinal Plants olea europaea hypoglycaemic diabetes rat
author_facet	A Eidi M Eidi SH Oryan F Fallahyan R Darzi Darounkala
author_sort	A Eidi
title	Hypoglycaemic effect of alcoholic extract of olive (Olea europaea L.) leaf in healthy and diabetic rats
title_short	Hypoglycaemic effect of alcoholic extract of olive (Olea europaea L.) leaf in healthy and diabetic rats
title_full	Hypoglycaemic effect of alcoholic extract of olive (Olea europaea L.) leaf in healthy and diabetic rats
title_fullStr	Hypoglycaemic effect of alcoholic extract of olive (Olea europaea L.) leaf in healthy and diabetic rats
title_full_unstemmed	Hypoglycaemic effect of alcoholic extract of olive (Olea europaea L.) leaf in healthy and diabetic rats
title_sort	hypoglycaemic effect of alcoholic extract of olive (olea europaea l.) leaf in healthy and diabetic rats
publisher	Institue of Medicinal Plants, ACECR
series	Journal of Medicinal Plants
issn	2717-204X 2717-2058
publishDate	2004-11-01
description	In traditional medicine leaves of olive (Olea europaea L.) are used as a diuretic, hypotensive, antibacterial and antiatherosclerotic. In the present study, oral administration of 0.1, 0.25 and 0.5g/kg body wt. of the alcoholic extract of leaves of olive for 14 days on the level of glucose and insulin in healthy and streptozotocin-induced diabetic rats were evaluated. The results showed that oral administration of the alcoholic extract of olive exhibited a significant reduction in blood glucose and increased plasma insulin in diabetic rats. The extract didnot change the level of blood glucose and plasma insulin in healthy rats significantly. A comparison was made between the action of the alcoholic extract and a known antidiabetic drug, glibenclamide (600 g/kg body wt.). The hypoglycaemic effect of the extract was greater than that observed with glibenclamide.
topic	olea europaea hypoglycaemic diabetes rat
url	http://jmp.ir/article-1-726-en.html
work_keys_str_mv	AT aeidi hypoglycaemiceffectofalcoholicextractofoliveoleaeuropaealleafinhealthyanddiabeticrats AT meidi hypoglycaemiceffectofalcoholicextractofoliveoleaeuropaealleafinhealthyanddiabeticrats AT shoryan hypoglycaemiceffectofalcoholicextractofoliveoleaeuropaealleafinhealthyanddiabeticrats AT ffallahyan hypoglycaemiceffectofalcoholicextractofoliveoleaeuropaealleafinhealthyanddiabeticrats AT rdarzidarounkala hypoglycaemiceffectofalcoholicextractofoliveoleaeuropaealleafinhealthyanddiabeticrats
_version_	1717376518828589056

Hypoglycaemic effect of alcoholic extract of olive (Olea europaea L.) leaf in healthy and diabetic rats

Similar Items