Spatial memory deficits after vincristine-induced lesions to the dorsal hippocampus.

Vincristine is a commonly used cytostatic drug for the treatment of leukemia, neuroblastoma and lung cancer, which is known to have neurotoxic properties. The aim of this study was to assess the effects of vincristine, injected directly into the dorsal hippocampus, in spatial memory using the spatia...

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Bibliographic Details
Main Authors: Daniela M Meléndez, Rebecca E Nordquist, Louk J M J Vanderschuren, Franz-Josef van der Staay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231941