Optimization of Hyperglycemic Induction in Zebrafish and Evaluation of Its Blood Glucose Level and Metabolite Fingerprint Treated with <i>Psychotria malayana</i> Jack Leaf Extract

Optimization of Hyperglycemic Induction in Zebrafish and Evaluation of Its Blood Glucose Level and Metabolite Fingerprint Treated with <i>Psychotria malayana</i> Jack Leaf Extract

A standard protocol to develop type 1 diabetes in zebrafish is still uncertain due to unpredictable factors. In this study, an optimized protocol was developed and used to evaluate the anti-diabetic activity of <i>Psychotria malayana</i> leaf. The aims of this study were to develop a typ...

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Bibliographic Details
Main Authors: Khaled Benchoula, Alfi Khatib, Fairuz M. C. Quzwain, Che Anuar Che Mohamad, Wan Mohd Azizi Wan Sulaiman, Ridhwan Abdul Wahab, Qamar Uddin Ahmed, Majid Abdul Ghaffar, Mohd Zuwairi Saiman, Mohamed F. Alajmi, Hesham El-Seedi
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Molecules
Subjects:
Type 1 diabetes
zebrafish
<i>Psychotria malayana</i>
alloxan
insulin
streptozotocin
Online Access:https://www.mdpi.com/1420-3049/24/8/1506

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