Cardiac Overexpression of XIN Prevents Dilated Cardiomyopathy Caused by TNNT2 ΔK210 Mutation

Cardiac Overexpression of XIN Prevents Dilated Cardiomyopathy Caused by TNNT2 ΔK210 Mutation

TNNT2 mutation is associated with a range of cardiac diseases, including dilated cardiomyopathy (DCM). However, the mechanisms underlying the development of DCM and heart failure remain incompletely understood. In the present study, we found the expression of cardiac XIN protein was reduced in TNNT2...

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Bibliographic Details
Main Authors: Bin Li, Yifan Guo, Yongkun Zhan, Xinyan Zhou, Yongbo Li, Chao Zhao, Ning Sun, Chen Xu, Qianqian Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
dilated cardiomyopathy
gene therapy
TNNT2
cardiac remodeling
XIN
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.691749/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.691749/full

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