Systemic effector and regulatory immune responses to chlamydial antigens in Trachomatous Trichiasis

Systemic effector and regulatory immune responses to chlamydial antigens in Trachomatous Trichiasis

Trachomatous trichiasis (TT) caused by repeated or chronic ocular infection with Chlamydia trachomatis is the result of a pro-fibrotic ocular immune response. At the conjunctiva the increased expression of both inflammatory (IL1Β, TNF) and regulatory cytokines (IL10) have been associated with advers...

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Bibliographic Details
Main Authors: Alevtina eGall, Amir eHorowitz, Hassan eJoof, Angels eNatividad, Kevin eTetteh, Eleanor eRiley, Robin L Bailey, David CW Mabey, Martin J Holland
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Chlamydia trachomatis
Interferon-gamma
Trachoma
NK cells
immune response
Tregs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00010/full

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