Lineage-specific restraint of pituitary gonadotroph cell adenoma growth.

Lineage-specific restraint of pituitary gonadotroph cell adenoma growth.

Although pituitary adenomas are usually benign, unique trophic mechanisms restraining cell proliferation are unclear. As GH-secreting adenomas are associated with p53/p21-dependent senescence, we tested mechanisms constraining non-functioning pituitary adenoma growth. Thirty six gonadotroph-derived...

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Bibliographic Details
Main Authors: Vera Chesnokova, Svetlana Zonis, Cuiqi Zhou, Anat Ben-Shlomo, Kolja Wawrowsky, Yoel Toledano, Yunguang Tong, Kalman Kovacs, Bernd Scheithauer, Shlomo Melmed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3064664?pdf=render

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http://europepmc.org/articles/PMC3064664?pdf=render

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