Research advances in non-hormonal therapies for autoimmune hepatitis

• Main Authors: ZHONG Qihua, ZHOU Guiqin, WANG Xianbo
• Format: Article
• Language: zho
• Published: Editorial Department of Journal of Clinical Hepatology 2016-02-01
• Series: Linchuang Gandanbing Zazhi
• Subjects: hepatitis; autoimmune; immunosuppressive agents; TCM WM therapy; review
• Online Access: http://www.lcgdbzz.org/qk_content.asp?id=7168

Autoimmune hepatitis is a chronic progressive inflammatory disease of the liver, which is mediated by the abnormal autoimmune response. Immunosuppressive therapy is the major therapeutic method for this disease, and liver transplantation can be performed for patients in the advanced stage. At present, the internationally acknowledged standard therapeutic method is prednisone or prednisone combined with azathioprine. Most patients can achieve clinical remission, but the recurrence rate is high and some patients fail to respond to the treatment. This article briefly reviews the therapies except corticosteroid therapy and substitutive therapy after treatment failure, introduces the application of integrated traditional Chinese and Western medicine therapy for autoimmune hepatitis, and points out that non-hormonal therapies are the new directions for the treatment of autoimmune hepatitis, which still needs to be further investigated.