Research advances in non-hormonal therapies for autoimmune hepatitis

Autoimmune hepatitis is a chronic progressive inflammatory disease of the liver, which is mediated by the abnormal autoimmune response. Immunosuppressive therapy is the major therapeutic method for this disease, and liver transplantation can be performed for patients in the advanced stage. At presen...

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Bibliographic Details
Main Authors: ZHONG Qihua, ZHOU Guiqin, WANG Xianbo
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2016-02-01
Series:Linchuang Gandanbing Zazhi
Subjects:
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=7168
Description
Summary:Autoimmune hepatitis is a chronic progressive inflammatory disease of the liver, which is mediated by the abnormal autoimmune response. Immunosuppressive therapy is the major therapeutic method for this disease, and liver transplantation can be performed for patients in the advanced stage. At present, the internationally acknowledged standard therapeutic method is prednisone or prednisone combined with azathioprine. Most patients can achieve clinical remission, but the recurrence rate is high and some patients fail to respond to the treatment. This article briefly reviews the therapies except corticosteroid therapy and substitutive therapy after treatment failure, introduces the application of integrated traditional Chinese and Western medicine therapy for autoimmune hepatitis, and points out that non-hormonal therapies are the new directions for the treatment of autoimmune hepatitis, which still needs to be further investigated.
ISSN:1001-5256
1001-5256