Fabrication, Modeling and Characterization of Multi-Crosslinked Methacrylate Copolymeric Nanoparticles for Oral Drug Delivery

Fabrication, Modeling and Characterization of Multi-Crosslinked Methacrylate Copolymeric Nanoparticles for Oral Drug Delivery

Nanotechnology remains the field to explore in the quest to enhance therapeutic efficacies of existing drugs. Fabrication of a methacrylate copolymer-lipid nanoparticulate (MCN) system was explored in this study for oral drug delivery of levodopa. The nanoparticles were fabricated employing multicro...

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Bibliographic Details
Main Authors: Riaz A. Khan, Viness Pillay, Valence M.K. Ndesendo, Pradeep Kumar, Lisa C. du Toit, Dinesh Naidoo, Yahya E. Choonara, Girish Modi, Ndidi C. Ngwuluka
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:International Journal of Molecular Sciences
Subjects:
nanotechnology
nanoparticles
nanocapsules
methacrylate copolymer
chitosan
oral drug delivery
bioavailability
crosslinking
molecular mechanics simulations
Online Access:http://www.mdpi.com/1422-0067/12/9/6194/

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http://www.mdpi.com/1422-0067/12/9/6194/

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