Overexpression of myeloid differentiation protein 88 in mice induces mild cardiac dysfunction, but no deficit in heart morphology

Overexpression of myeloid differentiation protein 88 in mice induces mild cardiac dysfunction, but no deficit in heart morphology

Cardiac remodeling involves changes in heart shape, size, structure, and function after injury to the myocardium. The proinflammatory adaptor protein myeloid differentiation protein 88 (MyD88) contributes to cardiac remodeling. To investigate whether excessive MyD88 levels initiate spontaneous cardi...

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Bibliographic Details
Main Authors:	W. Chen, Z. Huang, X. Jiang, C. Li, X. Gao
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2016-01-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Cardiac dysfunction Cardiac remodeling Transgenic mice Myeloid differentiation protein 88
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000100605&lng=en&tlng=en

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