The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment.

The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment.

Women with advanced maternal age exhibit low anti-Müllerian hormone (AMH) levels and an altered follicular environment, which is associated with poor oocyte quality and embryonic developmental potential. However, the underlying mechanism is poorly understood. The present study aimed to assesswhether...

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Bibliographic Details
Main Authors: Xu-Lei Sun, Hao Jiang, Dong-Xu Han, Yao Fu, Jian-Bo Liu, Yan Gao, Shu-Min Hu, Bao Yuan, Jia-Bao Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6147527?pdf=render

Internet

http://europepmc.org/articles/PMC6147527?pdf=render

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