The RNA interactome of human telomerase RNA reveals a coding-independent role for a histone mRNA in telomere homeostasis

The RNA interactome of human telomerase RNA reveals a coding-independent role for a histone mRNA in telomere homeostasis

Telomerase RNA (TR) provides the template for DNA repeat synthesis at telomeres and is essential for genome stability in continuously dividing cells. We mapped the RNA interactome of human TR (hTR) and identified a set of non-coding and coding hTR-interacting RNAs, including the histone 1C mRNA (HIS...

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Bibliographic Details
Main Authors: Roland Ivanyi-Nagy, Syed Moiz Ahmed, Sabrina Peter, Priya Dharshana Ramani, Peh Fern Ong, Oliver Dreesen, Peter Dröge
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-10-01
Series:eLife
Subjects:
telomeres
telomerase RNA
non-coding RNA
RNA-RNA interactions
telomere homeostasis
Online Access:https://elifesciences.org/articles/40037

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