Ganglioside Monosialic Acid Alleviates Peripheral Neuropathy Induced by Utidelone Plus Capecitabine in Metastatic Breast Cancer From a Phase III Clinical Trial

Ganglioside Monosialic Acid Alleviates Peripheral Neuropathy Induced by Utidelone Plus Capecitabine in Metastatic Breast Cancer From a Phase III Clinical Trial

PurposeThis study aimed to assess the efficacy of utidelone, a novel genetically engineered epothilone analog, combined with capecitabine in our center and, furthermore, to identify whether ganglioside monosialic acid (GM1) improved chemotherapy-induced peripheral neurotoxicity (CIPN).MethodsFifty-f...

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Bibliographic Details
Main Authors: Junnan Xu, Yan Wang, Cui Jiang, Hui Cao, Junhan Jiang, Binghe Xu, Tao Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
Ganglioside monosialic acid
capecitabine
chemotherapy-induced peripheral neurotoxicity
metastatic breast cancer
Utidelone
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.524223/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.524223/full

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