Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic
T cell responses are known to be essential in the immune response to Ebola virus infection, and the viral glycoprotein is a major antigenic target. Here the authors provide fine detail mapping of T cell antigens and their characterisation in Ebola virus survivor patients.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2021-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-21411-0 |
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doaj-e6b0735d435f48e18929d44dd2c3bb842021-02-21T12:12:56ZengNature Publishing GroupNature Communications2041-17232021-02-011211910.1038/s41467-021-21411-0Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemicT. R. W. Tipton0Y. Hall1J. A. Bore2A. White3L. S. Sibley4C. Sarfas5Y. Yuki6M. Martin7S. Longet8J. Mellors9K. Ewer10S. Günther11M. Carrington12M. K. Kondé13M. W. Carroll14National Infection Service, Public Health EnglandNational Infection Service, Public Health EnglandCenter for Training and Research on Priority Diseases including Malaria in Guinea (CEFORPAG)National Infection Service, Public Health EnglandNational Infection Service, Public Health EnglandNational Infection Service, Public Health EnglandBasic Science Program, Frederick National Laboratory for Cancer Research in the Laboratory of Integrative Cancer Immunology, National Cancer InstituteBasic Science Program, Frederick National Laboratory for Cancer Research in the Laboratory of Integrative Cancer Immunology, National Cancer InstituteNational Infection Service, Public Health EnglandNational Infection Service, Public Health EnglandThe Jenner InstituteBernhard Nocht Institute for Tropical MedicineBasic Science Program, Frederick National Laboratory for Cancer Research in the Laboratory of Integrative Cancer Immunology, National Cancer InstituteCenter for Training and Research on Priority Diseases including Malaria in Guinea (CEFORPAG)National Infection Service, Public Health EnglandT cell responses are known to be essential in the immune response to Ebola virus infection, and the viral glycoprotein is a major antigenic target. Here the authors provide fine detail mapping of T cell antigens and their characterisation in Ebola virus survivor patients.https://doi.org/10.1038/s41467-021-21411-0 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
T. R. W. Tipton Y. Hall J. A. Bore A. White L. S. Sibley C. Sarfas Y. Yuki M. Martin S. Longet J. Mellors K. Ewer S. Günther M. Carrington M. K. Kondé M. W. Carroll |
| spellingShingle |
T. R. W. Tipton Y. Hall J. A. Bore A. White L. S. Sibley C. Sarfas Y. Yuki M. Martin S. Longet J. Mellors K. Ewer S. Günther M. Carrington M. K. Kondé M. W. Carroll Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic Nature Communications |
| author_facet |
T. R. W. Tipton Y. Hall J. A. Bore A. White L. S. Sibley C. Sarfas Y. Yuki M. Martin S. Longet J. Mellors K. Ewer S. Günther M. Carrington M. K. Kondé M. W. Carroll |
| author_sort |
T. R. W. Tipton |
| title |
Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic |
| title_short |
Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic |
| title_full |
Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic |
| title_fullStr |
Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic |
| title_full_unstemmed |
Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic |
| title_sort |
characterisation of the t-cell response to ebola virus glycoprotein amongst survivors of the 2013–16 west africa epidemic |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2021-02-01 |
| description |
T cell responses are known to be essential in the immune response to Ebola virus infection, and the viral glycoprotein is a major antigenic target. Here the authors provide fine detail mapping of T cell antigens and their characterisation in Ebola virus survivor patients. |
| url |
https://doi.org/10.1038/s41467-021-21411-0 |
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