Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic

T cell responses are known to be essential in the immune response to Ebola virus infection, and the viral glycoprotein is a major antigenic target. Here the authors provide fine detail mapping of T cell antigens and their characterisation in Ebola virus survivor patients.

Bibliographic Details
Main Authors: T. R. W. Tipton, Y. Hall, J. A. Bore, A. White, L. S. Sibley, C. Sarfas, Y. Yuki, M. Martin, S. Longet, J. Mellors, K. Ewer, S. Günther, M. Carrington, M. K. Kondé, M. W. Carroll
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21411-0
Description
Summary:T cell responses are known to be essential in the immune response to Ebola virus infection, and the viral glycoprotein is a major antigenic target. Here the authors provide fine detail mapping of T cell antigens and their characterisation in Ebola virus survivor patients.
ISSN:2041-1723